Mutation of a Single Lytic Transglycosylase Causes Aberrant Septation and Inhibits Cell Separation of Neisseria gonorrhoeae-Reference-Cited by-同舟云学术

Mutation of a Single Lytic Transglycosylase Causes Aberrant Septation and Inhibits Cell Separation of Neisseria gonorrhoeae

Published:2004-11-15 Issue:22 Volume:186 Page:7811-7814
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Cloud Karen A.¹,Dillard Joseph P.¹

Affiliation:

1. Department of Medical Microbiology and Immunology, University of Wisconsin— Madison Medical School, Madison, Wisconsin

Abstract

ABSTRACT The function of lytic peptidoglycan transglycosylases is poorly understood. Single lytic transglycosylase mutants of Escherichia coli have no growth phenotype. By contrast, mutation of Neisseria gonorrhoeae ltgC inhibited cell separation without affecting peptidoglycan monomer production. Thus, LtgC has a dedicated function in gonococcal cell division.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.186.22.7811-7814.2004

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