Variable Expression of Opa Proteins by Neisseria gonorrhoeae Influences Bacterial Association and Phagocytic Killing by Human Neutrophils-Reference-Cited by-同舟云学术

Variable Expression of Opa Proteins by Neisseria gonorrhoeae Influences Bacterial Association and Phagocytic Killing by Human Neutrophils

Published:2022-04-19 Issue:4 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Alcott Allison M.¹,Werner Lacie M.¹,Baiocco Christopher M.¹,Belcher Dufrisne Meagan²,Columbus Linda²,Criss Alison K.¹^ORCID

Affiliation:

1. Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA

2. Department of Chemistry, University of Virginia, Charlottesville, Virginia, USA

Abstract

Neisseria gonorrhoeae , the cause of gonorrhea, is an urgent-threat pathogen due to increasing numbers of infections and increased antibiotic resistance. Many surface components of N. gonorrhoeae are phase variable, including the Opa protein family of adhesins and invasins.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

University of Virginia

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00035-22

Reference62 articles.

1. Opacity genes in Neisseria gonorrhoeae: Control of phase and antigenic variation