Affiliation:
1. Department of Microbiology and Infectious Disease, Toho University School of Medicine , Tokyo, Japan
Abstract
ABSTRACT
L1 metallo-β-lactamases produced by
Stenotrophomonas maltophilia
exhibit high diversity. Here, we characterized the genomes of
Stenotrophomonas
species harboring
bla
L1-like
genes using publicly available genome sequences. Our findings provide evidence that
Stenotrophomonas
species with
bla
L1-like
genes constitute a complex comprising many species with high genetic diversity, and similarities between
bla
L1-like
genes are lower than those of the genome. This suggests that the diversity of
bla
L1-like
is attributable to species diversity in
Stenotrophomonas
species harboring
bla
L1-like
and the rapid evolutionary changes in
bla
L1-like
genes.
Funder
Japan Society for the Promotion of Science
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology