Cytokine Receptor-Like Factor 3 Negatively Regulates Antiviral Immunity by Promoting the Degradation of TBK1 in Teleost Fish-Reference-Cited by-同舟云学术

Cytokine Receptor-Like Factor 3 Negatively Regulates Antiviral Immunity by Promoting the Degradation of TBK1 in Teleost Fish

Published:2023-01-31 Issue:1 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Yan Xiaolong¹,Zheng Weiwei¹,Geng Shang¹,Zhou Ming¹,Xu Tianjun¹²³⁴^ORCID

Affiliation:

1. Laboratory of Fish Molecular Immunology, College of Fisheries and Life Science, Shanghai Ocean University, Shanghai, China

2. Laboratory of Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

3. Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources (Shanghai Ocean University), Ministry of Education, Shanghai, China

4. National Pathogen Collection Center for Aquatic Animals, Shanghai Ocean University, Shanghai, China

Abstract

The expression of Crlf3 was upregulated with SCRV invasion, which proved that Crlf3 was involved in the regulation of the antiviral immune response. In this study, we found that the existence of Crlf3 promoted the replication of SCRV.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01792-22

Reference48 articles.

1. Pathogen Recognition and Innate Immunity

2. Pattern Recognition Receptors and Inflammation

3. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

4. Structural Mechanism of RNA Recognition by the RIG-I-like Receptors

5. Immune Signaling by RIG-I-like Receptors

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