Antimicrobial Activity of Novel Furanonaphthoquinone Analogs-Reference-Cited by-同舟云学术

Antimicrobial Activity of Novel Furanonaphthoquinone Analogs

Published:1998-03 Issue:3 Volume:42 Page:700-702
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Nagata Kumiko¹,Hirai Kei-Ichi²,Koyama Junko³,Wada Yasunao⁴,Tamura Toshihide¹

Affiliation:

1. Department of Bacteriology1 and

2. Department of Anatomy, Kanazawa Medical University, Uchinada, Ishikawa 920-02,2 and

3. Kobe Pharmaceutical University, Motoyamakita-machi, Higashinada-ku, Kobe 658,3 Japan

4. Clinical Laboratory,4 Hyogo College of Medicine, Nishinomiya, Hyogo 663,

Abstract

ABSTRACT Analogs of furanonaphthoquinone (FNQ) from Tecoma ipe Mart had MICs ranging from 1.56 to 25 μg/ml against gram-positive bacteria. FNQ showed significantly lower MICs against methicillin-resistant Staphylococcus aureus than against methicillin-sensitive S. aureus . FNQ inhibited Helicobacter pylori with an MIC of 0.1 μg/ml. Fungi, including pathogenic species, were sensitive to FNQ with MICs similar to those of amphotericin B.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.42.3.700

Reference16 articles.

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