CMY-13, a Novel Inducible Cephalosporinase Encoded by an Escherichia coli Plasmid-Reference-Cited by-同舟云学术

CMY-13, a Novel Inducible Cephalosporinase Encoded by an Escherichia coli Plasmid

Published:2004-08 Issue:8 Volume:48 Page:3172-3174
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Miriagou V.¹,Tzouvelekis L. S.¹²,Villa L.³,Lebessi E.¹,Vatopoulos A. C.⁴,Carattoli A.³,Tzelepi E.¹

Affiliation:

1. Laboratory of Bacteriology, Hellenic Pasteur Institute

2. Department of Microbiology, Medical School, University of Athens

3. Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy

4. Microbiology Division, National School of Public Health, Athens, Greece

Abstract

ABSTRACT An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii -derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS 26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.8.3172-3174.2004

Reference21 articles.

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