Author:
Valtonen V V,Sarvas M,Mäkelä P H
Abstract
The T2 antigenic form of Salmonella bareilly was examined. The absence of O specificity in this strain was shown to be due to its nonfunctional rfb genes; when the rfb gene cluster was replaced by the rfb cluster derived from smooth donor strains, T2,S and T2,SR recombinants were produced that expressed both T2 and either 0-6,7 or 0-4,12 specificity, depending on O antigen of the donor strain. The T2, T2,S, and T2,SR forms were all unstable on culture and segregated T2-negative forms (R, S, and SR, respectively) at a high rate. In all these respects the T2 antigen closely resembled the other T-form antigen, T1. The genes responsible for the T2 antigen, rfu, were not close to rfb, but their precise location and relation to rft (which determines T1 antigen) could not be discovered because of the instability to the T2 form and low recombination frequency in the necessary interspecies crosses.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference24 articles.
1. Structural investigation on TI lipopolysaccharides;Berst M.;Eur. J. Biochem.,1969
2. Structural investigations on the-Salmonella T2 lipopolysaccharide;Bruneteau M.;Eur. J. Biochem.,1974
3. A new antigen of Salmonella paratyphi B and Salmonella typhimurium;Kauffmann F.;Acta Pathol. Microbiol. Scand.,1956
4. On the T antigen of Salmonella bareilly;Kauffmann F.;Acta Pathol. Microbiol. Scand.,1957
5. Kauffmann F. 1966. The bacteriology of enterobacteriaceae. Munksgaard Copenhagen.
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献