Induction of Transmucosal Protection by Oral Vaccination with an Attenuated Chlamydia-Reference-Cited by-同舟云学术

Induction of Transmucosal Protection by Oral Vaccination with an Attenuated Chlamydia

Published:2023-05-16 Issue:5 Volume:91 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Wang Yihui¹²,He Rongze¹²,Winner Halah²,Gauduin Marie-Claire³,Zhang Nu²,He Cheng¹,Zhong Guangming²^ORCID

Affiliation:

1. Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China

2. Department of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, Texas, USA

3. Department of Virology, Texas Biomedical Research Institute, San Antonio, Texas, USA

Abstract

Chlamydia muridarum has been used to study chlamydial pathogenesis because it induces mice to develop hydrosalpinx, a pathology observed in C. trachomatis -infected women. We identified a C. muridarum mutant that is no longer able to induce hydrosalpinx.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.00043-23

Reference57 articles.

1. CDC. 2017. Sexually transmitted disease surveillance 2016. Services USDoHaH Atlanta GA. https://www.cdc.gov/std/stats16/default.htm.

2. Chlamydia trachomatis Antigens Recognized in Women With Tubal Factor Infertility, Normal Fertility, and Acute Infection

3. National Institute of Allergy and Infectious Diseases workshop report: “Chlamydia vaccines: The way forward”