Recent Advances in Oral Vaccines for Animals

Author:

Zhong Kaining1,Chen Xinting1,Zhang Junhao1,Jiang Xiaoyu1,Zhang Junhui1,Huang Minyi1,Bi Shuilian2,Ju Chunmei13,Luo Yongwen13ORCID

Affiliation:

1. College of Veterinary Medicine, South China Agricultural University, Guangzhou 510640, China

2. School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, China

3. Key Laboratory of Animal Vaccine Development of the Ministry of Agriculture and Rural Affairs, South China Agricultural University, Guangzhou 510640, China

Abstract

Compared to traditional injected vaccines, oral vaccines offer significant advantages for the immunization of livestock and wildlife due to their ease of use, high compliance, improved safety, and potential to stimulate mucosal immune responses and induce systemic immunity against pathogens. This review provides an overview of the delivery methods for oral vaccines, and the factors that influence their immunogenicity. We also highlight the global progress and achievements in the development and use of oral vaccines for animals, shedding light on potential future applications in this field.

Funder

Guangdong Basic and Applied Basic Research Foundation

Publisher

MDPI AG

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