Antiherpesviral activity and inhibitory action on cell growth of 5-alkenyl derivatives of 1-beta D-arabinofuranosyluracil

Author:

Machida H,Kuninaka A,Yoshino H,Ikeda K,Mizuno Y

Abstract

Antiherpesviral activity of 5-vinyl-1-beta-D-arabinofuranosyluracil was as high as that of 1-beta-D-arabinofuranosylthymine, whereas the former was less inhibitory to cell growth than the latter. 5-Propenyl- and 5-butenyl-1-beta-D-arabinofuranosyluracil were less active than 5-vinyl-1-beta-D-arabinofuranosyluracil.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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