Affiliation:
1. Division of Microbiology, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Ontario, Canada
Abstract
Phenethyl β-
d
-galactopyranoside (PEG) was hydrolyzed by the β-galactosidase of
Escherichia coli
to form the toxic product phenethyl alcohol.
Salmonella typhimurium
did not hydrolyze PEG. In mixed culture, the ratio of
S. typhimurium
to
E. coli
was increased by growing the organisms in lactose broth containing 2.5% PEG. The high concentration of PEG required for inhibition of
E. coli
can be attributed to inadequate cell permeability rather than to prevention of β-galactosidase induction.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
1 articles.
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