Virulence of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa In Vitro and In Vivo-Reference-Cited by-同舟云学术

Virulence of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa In Vitro and In Vivo

Published:2004-05 Issue:5 Volume:48 Page:1876-1878
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Aoki S.¹²,Hirakata Y.¹²,Kondoh A.¹²,Gotoh N.³,Yanagihara K.²,Miyazaki Y.²,Tomono K.²,Yamada Y.¹,Kohno S.²,Kamihira S.¹

Affiliation:

1. Department of Laboratory Medicine

2. Second Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501

3. Department of Microbiology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan

Abstract

ABSTRACT We evaluated the virulence of Pseudomonas aeruginosa carrying bla IMP , a metallo-β-lactamase gene, and the efficacy of ceftazidime, imipenem-cilastatin, and ciprofloxacin in the endogenous bacteremia model. The presence of bla IMP did not practically change the virulence of the parent strain, and ciprofloxacin was effective against infection with P. aeruginosa carrying bla IMP .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.5.1876-1878.2004

Reference12 articles.

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3. Rapid Detection and Evaluation of Clinical Characteristics of Emerging Multiple-Drug-Resistant Gram-Negative Rods Carrying the Metallo-β-Lactamase Gene bla IMP

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