Transcriptional Response of Escherichia coli to TPEN

Author:

Sigdel Tara K.1,Easton J. Allen1,Crowder Michael W.1

Affiliation:

1. Department of Chemistry and Biochemistry, 160 Hughes Hall, Miami University, Oxford, Ohio 45056

Abstract

ABSTRACT DNA microarrays were used to probe the transcriptional response of Escherichia coli to N , N , N ′, N ′- tetrakis (2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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