Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci-Reference-Cited by-同舟云学术

Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci

Published:2014-02-27 Issue:1 Volume:2 Page:
ISSN:2169-8287
Container-title:Genome Announcements
language:en
Short-container-title:Genome Announc

Author:

Cohen-Gihon Inbar¹,Israeli Ofir¹,Beth-Din Adi¹,Levy Haim²,Cohen Ofer¹,Shafferman Avigdor¹,Zvi Anat¹,Chitlaru Theodor¹

Affiliation:

1. Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel

2. Department of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, Israel

Abstract

ABSTRACT We report the draft whole-genome sequence of the nonproteolytic Bacillus anthracis V770-NP1-R strain. Compared to those of other B. anthracis strains, the genome exhibits unique mutations in multiple targets potentially affecting proteolytic functions. One of these mutations is a deletion that disrupts the NprR quorum-sensing regulator of the NprA protease.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/genomeA.00075-14

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