RTX Toxin Actin Cross-Linking Activity in Clinical and Environmental Isolates of Vibrio cholerae-Reference-Cited by-同舟云学术

RTX Toxin Actin Cross-Linking Activity in Clinical and Environmental Isolates of Vibrio cholerae

Published:2007-07 Issue:7 Volume:45 Page:2289-2292
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Cordero Christina L.¹,Sozhamannan Shanmuga²,Satchell Karla J. Fullner¹

Affiliation:

1. Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611

2. Biological Defense Research Directorate, Naval Medical Research Center, Silver Spring, Maryland 20852

Abstract

ABSTRACT Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00349-07

Reference18 articles.

1. Bhattacharya, M. K., D. Dutta, S. K. Bhattacharya, A. Deb, A. K. Mukhopadhyay, G. B. Nair, T. Shimada, Y. Takeda, A. Chowdhury, and D. Mahalanabis. 1998. Association of a disease approximating cholera caused by Vibrio cholerae of serogroups other than O1 and O139. Epidemiol. Infect.120:1-5.

2. Chen, C. Y., K. M. Wu, Y. C. Chang, C. H. Chang, H. C. Tsai, T. L. Liao, Y. M. Liu, H. J. Chen, A. B. Shen, J. C. Li, T. L. Su, C. P. Shao, C. T. Lee, L. I. Hor, and S. F. Tsai. 2003. Comparative genome analysis of Vibrio vulnificus, a marine pathogen. Genome Res.13:2577-2587.

3. Detection of RTX Toxin Gene in Vibrio cholerae by PCR

4. Cordero, C. L., D. S. Kudryashov, E. Reisler, and K. J. Satchell. 2006. The actin cross-linking domain of the Vibrio cholerae RTX toxin directly catalyzes the covalent cross-linking of actin. J. Biol. Chem.281:32366-32374.

5. Clinical and Environmental Isolates of Vibrio cholerae Serogroup O141 Carry the CTX Phage and the Genes Encoding the Toxin-Coregulated Pili

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Secretome of Vibrio cholerae;Infections and Sepsis Development;2021-10-27

2. Chemical Strategies To Target Bacterial Virulence;Chemical Reviews;2017-02-24

3. Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers;Current Topics in Microbiology and Immunology;2016

4. Presence of virulence markers in environmental Vibrio vulnificus strains;Journal of Applied Microbiology;2013-03-06

5. Crystal Structure of the VgrG1 Actin Cross-linking Domain of the Vibrio cholerae Type VI Secretion System;Journal of Biological Chemistry;2012-11