Affiliation:
1. Department of Infectious Diseases, Medical Microbiology and Hygiene
2. Department of Internal Medicine I and Clinical Chemistry, University Hospital Heidelberg, Heidelberg, Germany
Abstract
ABSTRACT
We evaluated the fully automated molecular BD MAX Cdiff assay (BD Diagnostics) and the Xpert
C. difficile
test (Cepheid) for rapid detection of
Clostridium difficile
infection. Culture was done on chromogenic agar followed by matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry identification and toxin detection. Repeat testing was required for 1.8% and 6.0% of the BD MAX and Xpert tests, respectively. Sensitivities, specificities, positive predictive values (PPV), and negative predictive values (NPV) were 90.5%, 97.9%, 89.3%, and 98.1%, respectively, for BD MAX and 97.3%, 97.9%, 90.0%, and 99.5%, respectively, for Xpert.
Publisher
American Society for Microbiology
Cited by
43 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献