Characterization of a Divergent vanD -Type Resistance Element from the First Glycopeptide-Resistant Strain of Enterococcus faecium Isolated in Brazil-Reference-Cited by-同舟云学术

Characterization of a Divergent vanD -Type Resistance Element from the First Glycopeptide-Resistant Strain of Enterococcus faecium Isolated in Brazil

Published:2000-12 Issue:12 Volume:44 Page:3444-3446
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Dalla Costa Libera M.¹²,Reynolds Peter E.³,Souza Helena A. P. H. M.²,Souza Dilair C.²,Palepou Marie-France I.¹,Woodford Neil¹

Affiliation:

1. Antibiotic Resistance Monitoring and Reference Laboratory, Central Public Health Laboratory, London NW9 5HT,1 and

2. Hospital de Clinicas—Universidade Federal do Paraná, Curitiba, Paraná, Brazil2

3. Department of Biochemistry, University of Cambridge CB2 1QW,3 United Kingdom, and

Abstract

ABSTRACT Enterococcus faecium 10/96A from Brazil was resistant to vancomycin (MIC, 256 μg/ml) but gave no amplification products with primers specific for known van genotypes. A 2,368-bp fragment of a van cluster contained one open reading frame encoding a peptide with 83% amino acid identity to VanH D , and a second encoding a d -alanine- d -lactate ligase with 83 to 85% identity to VanD. The divergent glycopeptide resistance phenotype was designated VanD4.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.12.3444-3446.2000

Reference20 articles.

1. Characterization and modelling of VanT: a novel membrane-bound, serine racemase from vancomycin-resistant Enterococcus gallinarum BM4174.;Arias C. A.;Mol. Microbiol.,1999

2. Requirement of the VanY and VanX d,d-peptidases for glycopeptide resistant in enterococci.;Arthur M.;Mol. Microbiol.,1998

3. Molecular Characterization of the vanD Gene Cluster and a Novel Insertion Element in a Vancomycin-Resistant Enterococcus Isolated in Canada

4. Characterization of the vanD Glycopeptide Resistance Gene Cluster from Enterococcus faecium BM4339

5. Heterogeneity in the vanB Gene Cluster of Genomically Diverse Clinical Strains of Vancomycin-Resistant Enterococci

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