Identification and Comparison of the Sialic Acid-Binding Domain Characteristics of Avian Coronavirus Infectious Bronchitis Virus Spike Protein-Reference-Cited by-同舟云学术

Identification and Comparison of the Sialic Acid-Binding Domain Characteristics of Avian Coronavirus Infectious Bronchitis Virus Spike Protein

Published:2023-05-31 Issue:5 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

You Renrong¹²,Liu Kangchengyin¹²,Huang Min¹²,Tang Lihua¹²,Zhang Xuehui¹²,Huang Yahui¹²,Zhao Jing¹²,Zhao Ye¹²,Ye Lilin³,Zhang Guozhong¹²^ORCID

Affiliation:

1. National Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China

2. Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China

3. Institute of Immunology, Third Military Medical University, Chongqing, People’s Republic of China

Abstract

To date, only α-2,3-linked sialic acid has been identified as a potential host binding receptor for IBV. Here, we show the minimum region constituting the sialic acid binding domain (SABD) and the binding characteristics of the S1 subunit of spike (S) protein of IBV strains SD (GI-19), GD (GI-7), and M41 (GI-1) to various sialic acids.

Funder

MOST | National Key Research and Development Program of China

The 2115 Talent Development Program of China Agricultural University

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00489-23

Reference49 articles.

1. Human Coronavirus: Host-Pathogen Interaction

2. Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus