Affiliation:
1. Department of Chemical Engineering, North Carolina State University, Raleigh, North Carolina 27695-7905
Abstract
ABSTRACT
Collective transcriptional analysis of heat shock response in the hyperthermophilic archaeon
Pyrococcus furiosus
was examined by using a targeted cDNA microarray in conjunction with Northern analyses. Differential gene expression suggests that
P
.
furiosus
relies on a cooperative strategy of rescue (thermosome [Hsp60], small heat shock protein [Hsp20], and two VAT-related chaperones), proteolysis (proteasome), and stabilization (compatible solute formation) to cope with polypeptide processing during thermal stress.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
101 articles.
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