Affiliation:
1. Department of Microbiology, School of Medicine and Biomedical Sciences, State University of New York, Buffalo 14214.
Abstract
Bordetella bronchiseptica secreted a hydroxamate siderophore when grown in Fe-depleted medium. A Tn5lac insertion mutant of B. bronchiseptica, DBB22, did not produce this hydroxamate siderophore and was incapable of using lactoferrin as an Fe source. Our data suggest that B. bronchiseptica uses a siderophore for removal of Fe from lactoferrin and transferrin rather than relying upon a receptor for these host Fe-binding proteins.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
16 articles.
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2. Bordetella;Pathogenesis of Bacterial Infections in Animals;2010-05-12
3. Reduced Virulence of a
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Siderophore Mutant in Neonatal Swine;Infection and Immunity;2001-04
4. Lactoferrin;Natural Food Antimicrobial Systems;2000-06-21
5. About the Author;Lactoferrin;2000-06-09