Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model-Reference-Cited by-同舟云学术

Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Dhakal Santosh¹^ORCID,Ruiz-Bedoya Camilo A.²,Zhou Ruifeng¹,Creisher Patrick S.¹,Villano Jason S.³,Littlefield Kirsten¹,Ruelas Castillo Jennie⁴,Marinho Paula¹,Jedlicka Anne E.¹,Ordonez Alvaro A.²,Bahr Melissa²,Majewska Natalia⁵,Betenbaugh Michael J.⁵,Flavahan Kelly²,Mueller Alice R. L.¹,Looney Monika M.⁴,Quijada Darla⁴,Mota Filipa²,Beck Sarah E.³,Brockhurst Jacqueline³,Braxton Alicia M.³,Castell Natalie³,Stover Mitchel³,D’Alessio Franco R.⁴,Metcalf Pate Kelly A.³^ORCID,Karakousis Petros C.⁴,Mankowski Joseph L.³,Pekosz Andrew¹³^ORCID,Jain Sanjay K.²^ORCID,Klein Sabra L.¹^ORCID

Affiliation:

1. W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

2. Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

3. Department of Molecular and Comparative Pathobiology, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

4. Department of Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland, USA

5. Advanced Mammalian Biomanufacturing Innovation Center, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA

Abstract

Men experience more severe outcomes from coronavirus disease 2019 (COVID-19) than women. Golden Syrian hamsters were used to explore sex differences in the pathogenesis of a human clinical isolate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute on Aging

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00974-21

Reference62 articles.

1. Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

2. Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients

3. Estimating the burden of SARS-CoV-2 in France

4. GlobalHealth5050. The sex gender and COVID-19 project. https://globalhealth5050.org/the-sex-gender-and-covid-19-project/. Accessed 28 December 2020.

5. Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

Cited by 75 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control;Signal Transduction and Targeted Therapy;2024-09-11

2. Efficacy of molnupiravir and interferon for the treatment of SARS‐CoV‐2 in golden Syrian hamster;Journal of Medical Virology;2024-08-29

3. SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster;npj Viruses;2024-08-24

4. SARS-CoV-2 Rapidly Infects Peripheral Sensory and Autonomic Neurons, Contributing to Central Nervous System Neuroinvasion before Viremia;International Journal of Molecular Sciences;2024-07-28

5. Characterization of a SARS-CoV-2 Omicron BA.5 direct-contact transmission model in hamsters;2024-07-12