Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding Yeast-Reference-Cited by-同舟云学术

Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding Yeast

Published:2021-10-26 Issue:5 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bentley-DeSousa Amanda¹²,Downey Michael¹²^ORCID

Affiliation:

1. Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada

2. Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, Ontario, Canada

Abstract

Long polymers of inorganic phosphates called polyphosphates are ubiquitous across biological kingdoms. From bacteria to humans, they have diverse functions related to protein homeostasis, energy metabolism, and cell signaling.

Funder

Canadian Institute of Health Research

Ontario Ministry of Innovation and Research

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00994-21

Reference75 articles.

1. Inorganic Polyphosphate: Essential for Growth and Survival

2. Bacterial polyphosphates interfere with the innate host defense to infection

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4. Polyphosphate Is a Primordial Chaperone

5. The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation

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