Age-Related Changes in Expression of CXCR4 and CCR5 on Peripheral Blood Leukocytes from Uninfected Infants Born to Human Immunodeficiency Virus Type 1-Infected Mothers-Reference-Cited by-同舟云学术

Age-Related Changes in Expression of CXCR4 and CCR5 on Peripheral Blood Leukocytes from Uninfected Infants Born to Human Immunodeficiency Virus Type 1-Infected Mothers

Published:2004-01 Issue:1 Volume:11 Page:229-234
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Shalekoff Sharon¹²³,Gray Glenda E.¹²³,Tiemessen Caroline T.¹²³

Affiliation:

1. AIDS Virus Research Unit, National Institute for Communicable Diseases, and Department of Virology

2. University of the Witwatersrand, Johannesburg

3. Perinatal HIV Research Unit, Chris Hani-Baragwanath Hospital, Soweto, South Africa

Abstract

ABSTRACT Cross-sectional analysis of human immunodeficiency virus-exposed, uninfected infants revealed high proportions of CXCR4-expressing cells in their cord blood, which declined at 4.5 months and increased between 9 and 15 months to levels approaching those of uninfected adults. Proportions of CCR5-expressing cells, however, were very low in cord blood and subsequently increased with age.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.11.1.229-234.2004

Reference30 articles.

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