Clinical and Resistance Consequences of Misquantification of Plasma and Cerebrospinal Fluid Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Samples from an HIV-1 Subtype G-Infected Patient-Reference-Cited by-同舟云学术

Clinical and Resistance Consequences of Misquantification of Plasma and Cerebrospinal Fluid Human Immunodeficiency Virus Type 1 (HIV-1) RNA in Samples from an HIV-1 Subtype G-Infected Patient

Published:2009-11 Issue:11 Volume:47 Page:3763-3764
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Delaugerre Constance¹,Denis Blandine²,Peytavin Gilles³,Palmer Pierre¹,Mourez Thomas¹,Le Goff Jerôme¹,Molina Jean-Michel²,Simon François¹

Affiliation:

1. Department of Virology, Saint-Louis Hospital-APHP, Paris, France

2. Department of Infectious Diseases, Saint-Louis Hospital-APHP, Paris, France

3. Department of Pharmacology, Bichat-Claude Bernard Hospital-APHP, Paris, France

Abstract

ABSTRACT Human immunodeficiency virus (HIV) load is the main marker used to monitor antiviral treatment efficacy and resistance. We report a case of underquantification of HIV type 1 (HIV-1) RNA in plasma and cerebrospinal fluid from an HIV-1 subtype G-infected woman, leading to delayed diagnosis of HIV encephalitis and to the emergence of drug resistance.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00206-09

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