Sequence Conservation of the Region Targeted by the Abbott RealTime HBV Viral Load Assay in Clinical Specimens-Reference-Cited by-同舟云学术

Sequence Conservation of the Region Targeted by the Abbott RealTime HBV Viral Load Assay in Clinical Specimens

Published:2013-04 Issue:4 Volume:51 Page:1260-1262
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Cloherty Gavin A.¹,Rhoads James¹,Young Thomas P.²,Parkin Neil T.³,Holzmayer Vera⁴,Yuen Lilly⁵,Mullen Carolyn¹

Affiliation:

1. Abbott Molecular, Des Plaines, Illinois, USA

2. University of California, San Francisco, San Francisco, California, USA

3. Data First Consulting, Belmont, California, USA

4. Abbott Diagnostics, Abbott Park, Illinois, USA

5. Evivar Medical Pty. Ltd., Melbourne, Victoria, Australia

Abstract

ABSTRACT The Abbott RealTime HBV assay targets the N-terminal region of the S gene. Here we analyzed the sequence variability of the assay target region from >2,100 clinical specimens. Thermodynamic modeling of the percentage of bound primer/probe at the assay annealing temperature was performed to assess the potential effect of sequence variability.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.03003-12

Reference24 articles.

1. EASL clinical practice guidelines: management of chronic hepatitis B virus infection;European Association for the Study of the Liver;J. Hepatol,2012

2. Geographical and genetic diversity of the human hepatitis B virus;Kurbanov F;Hepatol. Res,2010

3. Hepatitis B virus genetic diversity;Echevarria JM;J. Med. Virol,2006

4. Hepatitis B virus genetic diversity and its impact on diagnostic assays;Hollinger FB;J. Viral Hepat,2007

5. Meeting the challenge of HIV diversity: strategies to mitigate the impact of HIV-1 genetic heterogeneity on performance of nucleic acid testing assays;Hackett J;Clin. Lab,2012

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