Activity of Daptomycin against Recent North American Isolates of Streptococcus pneumoniae-Reference-Cited by-同舟云学术

Activity of Daptomycin against Recent North American Isolates of Streptococcus pneumoniae

Published:2003-09 Issue:9 Volume:47 Page:2974-2977
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Restrepo M. I.¹,Velez J. A.¹,McElmeel M. L.²,Whitney C. G.³,Jorgensen J. H.¹²

Affiliation:

1. Departments of Medicine

2. Pathology, University of Texas Health Science Center, San Antonio, Texas 78229

3. Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333

Abstract

ABSTRACT Daptomycin MICs at which 50% of isolates were inhibited (MIC 50 s) and MIC 90 s determined by the NCCLS broth microdilution method were both 0.25 μg/ml (range, 0.06 to 2 μg/ml) for 350 pneumococcal isolates. MICs determined by E test strips on commercially prepared Mueller-Hinton sheep blood agars with different calcium contents were 2 to 3 dilutions higher than those determined by strips that contained daptomycin plus calcium. Daptomycin zone diameters varied little on the same media.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.9.2974-2977.2003

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