Author:
Brenciani Andrea,Tiberi Erika,Morici Eleonora,Oryaşın Erman,Giovanetti Eleonora,Varaldo Pietro E.
Abstract
ABSTRACTICESp1116, responsible forerm(B)-mediated, inducible erythromycin resistance inStreptococcus pyogenes, was comprehensively characterized, and its chromosomal integration site was determined. It displayed a unique mosaic organization consisting of a scaffold, related to TnGallo1 fromStreptococcus gallolyticus, with two inserted fragments separated by IS1216. One fragment, containingerm(B), displayed high-level identity to a portion of theS. pyogenesplasmid pSM19035; the other, containing a truncatedtet(M) gene, displayed high-level identity to the right-hand portion ofClostridium difficileTn5397.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
9 articles.
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