Use of Stored Serum from Uganda for Development and Evaluation of a Human Immunodeficiency Virus Type 1 Testing Algorithm Involving Multiple Rapid Immunoassays-Reference-Cited by-同舟云学术

Use of Stored Serum from Uganda for Development and Evaluation of a Human Immunodeficiency Virus Type 1 Testing Algorithm Involving Multiple Rapid Immunoassays

Published:2005-10 Issue:10 Volume:43 Page:5312-5315
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Singer Darrell E.¹²,Kiwanuka Noah³,Serwadda David⁴,Nalugoda Fred³,Hird Linda⁵,Bulken-Hoover Jamie⁵,Kigozi Godfrey³,Malia Jennifer A.¹²,Calero Eva K.¹²,Sateren Warren¹²,Robb Merlin L.²,Wabwire-Mangen Fred⁴,Wawer Maria⁶,Gray Ronald H.⁷,Sewankambo Nelson⁸,Birx Deborah L.¹²,Michael Nelson L.¹²

Affiliation:

1. Division of Retrovirology

2. U.S. Military HIV Research Program, Walter Reed Army Institute of Research, 1600 East Gude Drive, Rockville, Maryland 20850

3. Rakai Health Sciences Project, Kalisizo, Uganda

4. Institute of Public Health, College of Medicine, Makerere University, Kampala, Uganda

5. Uniformed Services University School of Medicine, Bethesda, Maryland 20814

6. Columbia University Mailman School of Public Health, New York City, New York 10032

7. Johns Hopkins University School of Public Health, Baltimore, Maryland 21215

8. College of Medicine, Makerere University, Kampala, Uganda

Abstract

ABSTRACT We report the development and evaluation of a human immunodeficiency virus type 1 testing algorithm consisting of three rapid antibody detection tests. Stored serum samples from Uganda were utilized with a final algorithm sensitivity of 100% and a specificity of 98.9% (95% confidence interval, 98.6% to 99.3%).

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.43.10.5312-5315.2005

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