Affiliation:
1. Institute for Bee Research, Friedrich-Engels-Str. 32, 16540 Hohen Neuendorf, Germany
2. Department of Entomology, Swedish University of Agricultural Sciences, Box 7044, 750 07 Uppsala, Sweden
Abstract
ABSTRACT
Virulence variations of
Paenibacillus larvae
subsp.
larvae
, the causative agent of American foulbrood disease of honeybees, were investigated by analysis of 16 field isolates of this pathogen, belonging to three previously characterized genotypes, as well as the type strain (ATCC 9545) of
P. larvae
subsp.
larvae
, with exposure bioassays. We demonstrated that the strain-specific 50% lethal concentrations varied within an order of magnitude and that differences in amount of time for the pathogen to kill 100% of the infected hosts (LT
100
) correlated with genotype. One genotype killed rather quickly, with a mean LT
100
of 7.8 ± 1.7 days postinfection, while the other genotypes acted more slowly, with mean LT
100
s of 11.2 ± 0.8 and 11.6 ± 0.6 days postinfection.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference20 articles.
1. Bailey, L., and B. V. Ball (ed). 1991. Honey bee pathology, 2nd ed., p. 51. Academic Press, Ltd., New York, N.Y.
2. Brodsgaard, C., W. Ritter, and H. Hansen. 1998. Response of in vitro reared honeybee larvae to various doses of Paenibacillus larvae larvae spores. Apidologie29:569-578.
3. Brodsgaard, C., H. Hansen, and W. Ritter. 2000. Progress of Paenibacillus larvae larvae infection in individually inoculated honeybee larvae reared singly in vitro, in micro colonies, or in full-size colonies. J. Apic. Res.39:19-27.
4. Chen, Y., C. Wang, J. An, K. Ho, Y. W. Chen, C. H. Wang, and K. K. Ho. 2000. Susceptibility of the Asian honey bee, Apis cerana, to American foulbrood, Paenibacillus larvae larvae. J. Apic. Res.39:169-175.
5. Ewald, P. W. 2002. Virulence management in humans, p. 399-412. In U. Dieckmann, J. A. J. Metz, M. W. Sabelis, and K. Sigmund (ed.), Adaptive dynamics of infectious diseases: in pursuit of virulence management. Cambridge University Press, Cambridge, United Kingdom.
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