Mechanism of Action of Anti-Influenza Benzamidine Derivatives

Author:

Fujita Haruhisa1,Seto Yoshiko1,Toyoshima Shigeshi1

Affiliation:

1. Pharmaceutical Institute, School of Medicine, Keio University, Shinano-cho, Shinjuku-ku, Tokyo 160, Japan

Abstract

Benzamidine derivatives exhibited a high antiviral effect in vivo against influenza virus strains A2/Adachi and B/Lee. The inhibiting properties of anti-influenza benzamidine derivatives on the virus-induced inflammation undoubtedly plays an important role in the clarification of the mechanism of action of these drugs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference16 articles.

1. Influenza virus growth and antibody response in amantadine treated mice;Davis W. L.;J. Immunol.,1965

2. Dual effect in the mechanism of action of anti-influenza virus amino acid analogues;Fujita H.;Antimicrob. Agents Chemother.,1973

3. Effect of amidine derivatives on influenza virus;Fujita H.;Prog. Antimicrob. Anticancer Chemother.,1969

4. Inhibitory effect of antiviral drugs on viral specific inflammatory factors produced with influenza virus;Fujita H.;Adv. Antimicrob. Antineoplast. Chemother.,1971

5. Suppression of influenza viral pneumonia in mice by the nonspecific action of zerosine;Ginsberg H. S.;J. Immunol.,1955

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. An update on small molecule strategies targeting leishmaniasis;European Journal of Medicinal Chemistry;2018-09

2. N-alpha-Cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen;Antimicrobial Agents and Chemotherapy;1979-09

3. Antiviral agents;Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques;1978

4. Therapeutic Effects of Ribavirin Given by the Intraperitoneal or Aerosol Route Against Influenza Virus Infections in Mice;Antimicrobial Agents and Chemotherapy;1976-09

5. Chapter 10: Antibiotics;Annual Reports in Medicinal Chemistry;1976

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3