The Sensor Histidine Kinase ArlS Is Necessary for Staphylococcus aureus To Activate ArlR in Response to Nutrient Availability-Reference-Cited by-同舟云学术

The Sensor Histidine Kinase ArlS Is Necessary for Staphylococcus aureus To Activate ArlR in Response to Nutrient Availability

Published:2021-11-19 Issue:24 Volume:203 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Párraga Solórzano Paola K.¹,Shupe Angela C.¹,Kehl-Fie Thomas E.¹²^ORCID

Affiliation:

1. Department of Microbiology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA

2. Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois, USA

Abstract

The ability of pathogens, including Staphylococcus aureus , to sense and adapt to diverse environments partially relies on two-component systems, such as ArlRS. Recent work revealed that the response regulator ArlR can be cross-activated by the sensor histidine kinase GraS, rendering the role of its cognate partner, ArlS, in response to manganese and glucose limitation uncertain.

Funder

Alice Helm Graduate Student Excellence Award

HHS | NIH | National Institute of Allergy and Infectious Diseases

Vallee Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.00422-21

Reference106 articles.

1. Two-Component Signal Transduction