Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots-Reference-Cited by-同舟云学术

Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots

Published:2021-09-27 Issue:20 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Teppor Mona¹,Žusinaite Eva¹,Karo-Astover Liis¹,Omler Ailar¹,Rausalu Kai¹,Lulla Valeria¹^ORCID,Lulla Aleksei¹,Merits Andres¹^ORCID

Affiliation:

1. Institute of Technology, University of Tartu, Tartu, Estonia

Abstract

Alphaviruses cause debilitating symptoms and have caused massive outbreaks. There are currently no approved antivirals or vaccines for treating these infections.

Funder

Estonian Research Council

Estonian Science Foundation

European Regional Development Fund via Centre of Excellence in Molecular Cell Engineering, Estonia

Institute of Technology, University of Tartu

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00973-21

Reference69 articles.