Characterization of an IncA/C Multidrug Resistance Plasmid in Vibrio alginolyticus-Reference-Cited by-同舟云学术

Characterization of an IncA/C Multidrug Resistance Plasmid in Vibrio alginolyticus

Published:2016-05 Issue:5 Volume:60 Page:3232-3235
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ye Lianwei¹²,Li Ruichao²³,Lin Dachuan²³,Zhou Yuanjie²³,Fu Aisi⁴,Ding Qiong⁴,Chan Edward Wai Chi²³,Yao Wen¹,Chen Sheng²³

Affiliation:

1. College of Animal Science and Technology, Nanjing Agriculture University, Nanjing, People's Republic of China

2. Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China

3. State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong

4. Wuhan Institute of Biotechnology, Wuhan, China

Abstract

ABSTRACT Cephalosporin-resistant Vibrio alginolyticus was first isolated from food products, with β-lactamases encoded by bla PER-1 , bla VEB-1 , and bla CMY-2 being the major mechanisms mediating their cephalosporin resistance. The complete sequence of a multidrug resistance plasmid, pVAS3-1, harboring the bla CMY-2 and qnrVC4 genes was decoded in this study. Its backbone exhibited genetic homology to known IncA/C plasmids recoverable from members of the family Enterobacteriaceae , suggesting its possible origin in Enterobacteriaceae .

Funder

973

FHB | Health and Medical Research Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00300-16

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2. Increasing Rates of Vibriosis in the United States, 1996–2010: Review of Surveillance Data From 2 Systems