Manipulating Fermentation Pathways in the Hyperthermophilic Archaeon Pyrococcus furiosus for Ethanol Production up to 95°C Driven by Carbon Monoxide Oxidation

Author:

Lipscomb Gina L.1,Crowley Alexander T.1,Nguyen Diep M. N.1,Keller Matthew W.1,O’Quinn Hailey C.1,Tanwee Tania N. N.1,Vailionis Jason L.2,Zhang Ke2,Zhang Ying2ORCID,Kelly Robert M.3ORCID,Adams Michael W. W.1ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA

2. Department of Cell and Molecular Biology, College of the Environment and Life Sciences, University of Rhode Island, Kingston, Rhode Island, USA

3. Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA

Abstract

Previously, the highest temperature for biological ethanol production was 85°C. Here, we have engineered ethanol production at 95°C by the hyperthermophilic archaeon Pyrococcus furiosus .

Funder

U.S. Department of Energy

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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