Suramin prevents duck hepatitis B virus infection in vivo-Reference-Cited by-同舟云学术

Suramin prevents duck hepatitis B virus infection in vivo

Published:1993-07 Issue:7 Volume:37 Page:1539-1542
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Offensperger W B¹,Offensperger S¹,Walter E¹,Blum H E¹,Gerok W¹

Affiliation:

1. Department of Medicine, University of Freiburg, Germany.

Abstract

The effect of suramin on duck hepatitis B virus (DHBV) infection was investigated in vivo. Suramin pretreatment of Pekin ducklings completely prevented DHBV infection. In contrast, suramin given at the time of or after inoculation with DHBV did not inhibit viral infection, replication, or gene expression. These data indicate that suramin effectively blocks the early stages of DHBV infection in vivo.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.37.7.1539

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