Ability of a Rapid Serology Test To Detect Seroconversion to Herpes Simplex Virus Type 2 Glycoprotein G Soon after Infection

Author:

Ashley Rhoda L.1,Eagleton Marie2,Pfeiffer Natasha1

Affiliation:

1. Department of Laboratory Medicine, University of Washington, Seattle, Washington,1 and

2. Diagnology Ltd., Belfast, Northern Ireland2

Abstract

ABSTRACT Sera ( n = 188) from 29 patients with first-episode genital herpes simplex virus type 2 (HSV-2) infections were tested by POCkit-HSV-2 and Western blot (WB) to determine the speed of seroconversion. The median time to detection of HSV-2 antibody was 13 days (range, 3 to 102 days) by the POCkit-HSV-2 test versus 13 days (range, 2 to 58 days) for WB.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference20 articles.

1. Inability of enzyme immunoassays to discriminate between infections with herpes simplex virus types 1 or 2;Ashley R.;Ann. Intern. Med.,1991

2. Ashley R. L. Current concepts of laboratory diagnosis of herpes simplex infection Clinical management of herpes viruses. Sacks S. L. Straus S. E. Whitley R. J. Griffiths P. D. 1995 137 171 IOS Press Washington D.C

3. Premarket Evaluation of a Commercial Glycoprotein G-Based Enzyme Immunoassay for Herpes Simplex Virus Type-Specific Antibodies

4. Ashley R. L. Pickering J. Pfeiffer N. Wei S. Wu L. Early diagnosis of first episode genital herpes simplex virus (HSV) infection by enzyme immunoassay (EIA) for type-specific IgM antibodies abstr. C-392 Abstracts of the 98th General Meeting of the American Society for Microbiology. 1998 196 American Society for Microbiology Washington D.C

5. Evaluation of a novel point-of-care test for antibodies to herpes simplex virus type 2;Ashley R. L.;Sex. Transm. Infect.,1998

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