Establishment of Canine RNA Polymerase I-Driven Reverse Genetics for Influenza A Virus: Its Application for H5N1 Vaccine Production-Reference-Cited by-同舟云学术

Establishment of Canine RNA Polymerase I-Driven Reverse Genetics for Influenza A Virus: Its Application for H5N1 Vaccine Production

Published:2008-02 Issue:3 Volume:82 Page:1605-1609
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Murakami Shin¹,Horimoto Taisuke¹²,Yamada Shinya¹²,Kakugawa Satoshi¹²,Goto Hideo¹²,Kawaoka Yoshihiro¹³²⁴

Affiliation:

1. Division of Virology, Department of Microbiology and Immunology

2. Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency, Saitama, Japan

3. International Research Center for Infectious Diseases, Institute of Medical Science, University of Tokyo, Tokyo, Japan

4. Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin

Abstract

ABSTRACT In the event of a new influenza pandemic, vaccines whose antigenicities match those of circulating strains must be rapidly produced. Here, we established an alternative reverse genetics system for influenza virus using the canine polymerase I (PolI) promoter sequence that works efficiently in the Madin-Darby canine kidney cell line, a cell line approved for human vaccine production. Using this system, we were able to generate H5N1 vaccine seed viruses more efficiently than can be achieved with the current system that uses the human PolI promoter in African green monkey Vero cells, thus improving pandemic vaccine production.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01876-07

Reference22 articles.

1. Brands, R., J. Visser, J. Medema, A. M. Palache, and G. J. van Scharrenburg. 1999. Influvac: a safe Madin Darby canine kidney (MDCK) cell culture-based influenza vaccine. Dev. Biol. Stand.98:93-100, 111.

2. de Wit, E., M. I. Spronken, G. Vervaet, G. F. Rimmelzwaan, A. D. Osterhaus, and R. A. Fouchier. 2007. A reverse-genetics system for influenza A virus using T7 RNA polymerase. J. Gen. Virol.88:1281-1287.

3. Rescue of Influenza A Virus from Recombinant DNA

4. Govorkova, E. A., S. Kodihalli, I. V. Alymova, B. Fanget, and R. G. Webster. 1999. Growth and immunogenicity of influenza viruses cultivated in Vero or MDCK cells and in embryonated chicken eggs. Dev. Biol. Stand.98:39-51, 73-74.

5. Halperin, S. A., B. Smith, T. Mabrouk, M. Germain, P. Trepanier, T. Hassell, J. Treanor, R. Gauthier, and E. L. Mills. 2002. Safety and immunogenicity of a trivalent, inactivated, mammalian cell culture-derived influenza vaccine in healthy adults, seniors, and children. Vaccine20:1240-1247.

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Identification of dihydroorotate dehydrogenase inhibitor, vidofludimus, as a potent and novel inhibitor for influenza virus;Journal of Medical Virology;2024-01

2. Investigating Influenza Virus Polymerase Activity in Feline Cells Based on the Influenza Virus Minigenome Replication System Driven by the Feline RNA Polymerase I Promoter;Frontiers in Immunology;2022-05-26

3. Influenza Reverse Genetics—Historical Perspective;Cold Spring Harbor Perspectives in Medicine;2020-01-21

4. Reverse Genetics for Peste des Petits Ruminants Virus: Current Status and Lessons to Learn from Other Non-segmented Negative-Sense RNA Viruses;Virologica Sinica;2018-11-19

5. A PB1-K577E Mutation in H9N2 Influenza Virus Increases Polymerase Activity and Pathogenicity in Mice;Viruses;2018-11-19