VIM-12, a Novel Plasmid-Mediated Metallo-β-Lactamase from Klebsiella pneumoniae That Resembles a VIM-1/VIM-2 Hybrid-Reference-Cited by-同舟云学术

VIM-12, a Novel Plasmid-Mediated Metallo-β-Lactamase from Klebsiella pneumoniae That Resembles a VIM-1/VIM-2 Hybrid

Published:2005-12 Issue:12 Volume:49 Page:5153-5156
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Pournaras Spyros¹,Ikonomidis Alexandros¹,Tzouvelekis Leonidas S.²,Tokatlidou Despoina³,Spanakis Nicholas²,Maniatis Antonios N.¹,Legakis Nicholas J.²,Tsakris Athanassios²

Affiliation:

1. Department of Microbiology, Medical School, University of Thessaly, Larissa

2. Department of Microbiology, Medical School, University of Athens, Athens

3. Department of Microbiology, Hippokration General Hospital, Thessaloniki, Greece

Abstract

ABSTRACT A transferable plasmid from Klebsiella pneumoniae carried a class 1 integron containing bla VIM-12 , a novel bla VIM -type gene, flanked by two copies of aacA7. bla VIM-12 was clustered between bla VIM-1 and bla VIM-2 and differed from bla VIM-1 by 18 nucleotides that were all located at the 3′ end and matched the corresponding nucleotides in bla VIM-2 . The bla VIM-12 -associated 59-base element was identical to that described in bla VIM-2 alleles.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.12.5153-5156.2005

Reference23 articles.

1. Arlet, G., and A. Philippon. 1991. Construction by polymerase chain reaction and use of intragenic DNA probes for three main types of transferable β-lactamases (TEM, SHV, CARB). FEMS Microbiol. Lett.66:19-25.

2. Docquier, J. D., J. Lamotte-Brasseur, M. Galleni, G. Amicosante, J.-M. Frere, and G. M. Rossolini. 2003. On functional and structural heterogeneity of VIM-type metallo-β-lactamases. J. Antimicrob. Chemother.51:257-266.

3. Standard Numbering Scheme for Class B β-Lactamases

4. VIM-1 Metallo-β-Lactamase-Producing Klebsiella pneumoniae Strains in Greek Hospitals

5. Cloning and Characterization of bla VIM , a New Integron-Borne Metallo-β-Lactamase Gene from a Pseudomonas aeruginosa Clinical Isolate

Cited by 33 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development of constitutive and IPTG-inducible integron promoter-based expression systems for Escherichia coli and Agrobacterium tumefaciens;3 Biotech;2023-02-20

2. VIM-encoding IncpSTY plasmids and chromosome-borne integrative and mobilizable elements (IMEs) and integrative and conjugative elements (ICEs) in Pseudomonas;Annals of Clinical Microbiology and Antimicrobials;2022-03-09

3. Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design;Chemical Reviews;2021-06-15

4. Protein determinants of dissemination and host specificity of metallo-β-lactamases;Nature Communications;2019-08-09

5. Ceftazidime Is the Key Diversification and Selection Driver of VIM-Type Carbapenemases;mBio;2018-07-05