Efficacy of Caspofungin against Aspergillus terreus-Reference-Cited by-同舟云学术

Efficacy of Caspofungin against Aspergillus terreus

Published:2005-12 Issue:12 Volume:49 Page:5133-5135
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Barchiesi Francesco¹,Spreghini Elisabetta¹,Santinelli Alfredo²,Fothergill Annette W.³,Fallani Stefania⁴,Manso Esther⁵,Pisa Eleonora²,Giannini Daniele⁶,Novelli Andrea⁴,Cassetta Maria I.⁴,Mazzei Teresita⁴,Rinaldi Michael G.³⁷,Scalise Giorgio¹

Affiliation:

1. Istituto di Malattie Infettive e Medicina Pubblica

2. Istituto di Anatomia Patologica

3. Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas

4. Istituto di Farmacologia Preclinica e Clinica, Università degli Studi di Firenze, Florence, Italy

5. Laboratorio di Microbiologia Azienda Ospedaliero-Universitaria Ospedali Riuniti Umberto I-Lancisi-Salesi, Ancona, Italy

6. Centro Gestione Presidenza Medicina e Chirurgia, Università Politecnica delle Marche

7. Audie L. Murphy Division, South Texas Veterans Health Care System, San Antonio, Texas

Abstract

ABSTRACT We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus . The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.12.5133-5135.2005

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