Binding of Aminoglycosides to Feces-Reference-Cited by-同舟云学术

Binding of Aminoglycosides to Feces

Published:1974-10 Issue:4 Volume:6 Page:415-417
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wagman Gerald H.¹,Bailey Janet V.¹,Weinstein Marvin J.¹

Affiliation:

1. Microbiology Division, Schering Corporation, Bloomfield, New Jersey 07003

Abstract

Gentamicin and several other basic antibiotics were examined for their ability to adsorb to dog feces. It was found that 44 to 90% of all antibiotics studied were adsorbed to feces depending on the ratio of antibiotic to fecal material. Attempts to extract these antibiotics by acid treatment after adsorption onto feces were only partially successful since large portions of the bound materials were not removed.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.6.4.415

Reference6 articles.

1. Binding of antibiotics to tissue homogenates;Kunin C. M.;J. Infect. Dis.,1970

2. Neomycin, a new intestinal antibiotic;Poth E. J.;Tex. Rep. Biol. Med.,1950

3. A critical analysis of neomycin as an antiseptic;Poth E. J.;Tex. Rep. Biol. Med.,1957

4. Binding of gentamicin and other aminoglycoside antibiotics to mycelium of various actinomycetes;Reiblein W. J.;Antimicrob. Ag. Chemother.,1973

5. Regeneration of antibiotic activity by deacetylation of N-acetyl derivatives of deoxystreptamine-containing antibiotics;Wagman G. H.;J. Med. Chem.,1964

Cited by 23 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Maximum levels of cross‐contamination for 24 antimicrobial active substances in non‐target feed. Part 2: Aminoglycosides/aminocyclitols: apramycin, paromomycin, neomycin and spectinomycin;EFSA Journal;2021-10

2. In vitro test systems to determine tetracycline residue binding to human feces;Regulatory Toxicology and Pharmacology;2018-11

3. An in vitro study to assess the impact of tetracycline on the human intestinal microbiome;Anaerobe;2018-02

4. An update discussion on the current assessment of the safety of veterinary antimicrobial drug residues in food with regard to their impact on the human intestinal microbiome;Drug Testing and Analysis;2016-05

5. Alternative Strategies for Proof-of-Principle Studies of Antibacterial Agents;Antimicrobial Agents and Chemotherapy;2014-05-27