Affiliation:
1. Department of Bacteriology, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
Abstract
An accurate plate diffusion bioassay for chloramphenicol is described, in which the fast-replicating
Beneckea natriegens
and 1.5% salt agar are used. Zones of inhibition were well defined after 3 h, and the limit of sensitivity of the method was around 2 μg/ml. The concurrent presence of gentamicin did not influence the assay. The assay is simple to carry out and duplicate assays can be performed with as little as 100 μg of capillary blood.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
17 articles.
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