Affiliation:
1. Department of Bacteriology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
Abstract
Depending on the hematocrit, duplicate or triplicate determinations of serum amphotericin B concentration may be made on as little as 100 μl of capillary blood obtained by finger prick. In an accurate plate diffusion bioassay, using
Paecilomyces varioti
as the indicator organism, levels of the drug in the therapeutic range can be determined fast enough for clinicians to modify their next dose.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
21 articles.
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