oqxAB Encoding a Multidrug Efflux Pump in Human Clinical Isolates of Enterobacteriaceae-Reference-Cited by-同舟云学术

oqxAB Encoding a Multidrug Efflux Pump in Human Clinical Isolates of Enterobacteriaceae

Published:2009-08 Issue:8 Volume:53 Page:3582-3584
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Kim Hong Bin¹²³,Wang Minghua³⁴,Park Chi Hye³,Kim Eui-Chong⁵,Jacoby George A.⁶,Hooper David C.³

Affiliation:

1. Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

2. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

3. Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts

4. Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China

5. Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea

6. Lahey Clinic, Burlington, Massachusetts

Abstract

ABSTRACT The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae . IS 26 -like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01574-08

Reference12 articles.

1. Development of PCR Assays Targeting the Genes Involved in Synthesis and Assembly of the New Escherichia coli O174 and O177 O Antigens

2. NorB, an Efflux Pump in Staphylococcus aureus Strain MW2, Contributes to Bacterial Fitness in Abscesses

3. Fouts, D. E., H. L. Tyler, R. T. DeBoy, S. Daugherty, Q. Ren, J. H. Badger, A. S. Durkin, H. Huot, S. Shrivastava, S. Kothari, R. J. Dodson, Y. Mohamoud, H. Khouri, L. F. W. Roesch, K. A. Krogfelt, C. Struve, E. W. Triplett, and B. A. Methé. 2008. Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice. PLoS Genet.4:e1000141.

4. Hansen, L. H., L. B. Jensen, H. I. Sørensen, and S. J. Sørensen. 2007. Substrate specificity of the OqxAB multidrug resistance pump in Escherichia coli and selected enteric bacteria. J. Antimicrob. Chemother.60:145-147.

5. Plasmid-Encoded Multidrug Efflux Pump Conferring Resistance to Olaquindox in Escherichia coli

Cited by 237 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Metagenomics Insight into Veterinary and Zoonotic Pathogens Identified in Urban Wetlands of Los Lagos, Chile;Pathogens;2024-09-12

2. Prevalence of plasmid-mediated quinolone resistance genes in extended-spectrum beta-lactamase producing Klebsiella pneumoniae isolates in northern Iran;Heliyon;2024-09

3. Mobile Colistin Resistance and Plasmid-Mediated Quinolone Resistance Genes in Escherichia coli from China, 1993–2019;Foodborne Pathogens and Disease;2024-07-01

4. Isolation of a PRD1-like phage uncovers the carriage of three putative conjugative plasmids in clinical Burkholderia contaminans;Research in Microbiology;2024-07

5. Short-chain fatty acids inhibit bacterial plasmid transfer through conjugation in vitro and in ex vivo chicken tissue explants;Frontiers in Microbiology;2024-06-06