Affiliation:
1. Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands
Abstract
The human gut microbial community is associated strongly with host physiology and human diseases. This observation has prompted research on pre- and probiotics, two concepts enabling specific changes in the composition of the human gut microbiome that result in beneficial effects for the host. Here, we show how fructooligosaccharide-inulin prebiotics are fermented by commercial probiotic bacterial strains involving specific sets of enzymes and transporters. Cross-feeding strains such as
Lactobacillus paracasei
W20 may thus act as keystone strains in the degradation of prebiotic inulin in the human gut, and this strain–
exo
-inulinase combination may be used in commercial
Lactobacillus
-inulin synbiotics.
Funder
Carbohydrate Competence Centre
University of Groningen
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology