Temporal study of immunoglobin M seroreactivity to Borrelia burgdorferi in patients treated for Lyme borreliosis

Author:

Hilton E1,Tramontano A1,DeVoti J1,Sood S K1

Affiliation:

1. Division of Clinical Research, Long Island Jewish Medical Center, the Long Island Campus for Albert Einstein College of Medicine, New Hyde Park, New York 11040, USA.

Abstract

Forty-six patients with late Lyme disease who were considered improved or cured following treatment were monitored by immunoglobin M (IgM) immunoblotting (mean monitoring period, 27.6 months). There was a persistent IgM response in 32 (97%) of 33 initially positive patients. All but three showed a consistent number, type, and intensity of IgM bands over the entire follow-up period. IgM immunoblotting may not be useful for monitoring the response to treatment of Lyme borreliosis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference13 articles.

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