In vitro cultivation of Treponema pallidum: independent confirmation

Author:

Norris S J

Abstract

In vitro cultivation of the virulent Nichols strain of Treponema pallidum was achieved in a tissue culture system as described by A. H. Fieldsteel, D. L. Cox, and R. A. Moeckli (Infect. Immun. 32:908-915, 1981). In 7 of 8 experiments, 8.9- to 26.2-fold increases in the number of T. pallidum were observed over a 12- to 12-day period of incubation.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference14 articles.

1. Virulent Treponema pallidum: aerobe or anaerobe;Baseman J. B.;Infect. Immun.,1976

2. The effects of reducing and other agents on the motility of Treponema pallidum in an aceliular culture medium;Chalmers W. S. K.;J. Gen. Microbiol.,1979

3. Oxygen uptake by Treponema pallidum;Cox C. D.;Infect. Immun.,1974

4. The rate of multiplication of Treponema pallidum in normal and immune rabbits;Cumberand M. C.;Am. J. Syph.,1949

5. Nutrition needs of mammalian cells in tissue culture;Eagle H.;Science,1955

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