Affiliation:
1. Venereal Disease Research Laboratory, National Communicable Disease Center, Public Health Service, Atlanta, Georgia 30333
Abstract
The passage of
Treponema pallidum
through commercially available Millipore membrane filters of various pore sizes was examined. No microscopically detectable organisms passed through a filter with a pore diameter of 0.22 μm. As pore size was increased, progressively more organisms passed through. Motile organisms passed through filters to a greater extent than nonmotile ones; however, 22% of the motile and 50% of the nonmotile
T. pallidum
organisms did not pass through the largest pore diameter tested (14.0 μm). Filtration of
T. pallidum
suspensions through membrane filters may offer a way of separating the organisms from larger particles of debris which accompany their extraction from rabbit testicular syphilomas.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference6 articles.
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