Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract

Author:

Lyon Laurie M.1ORCID,Doran Kelly S.1ORCID,Horswill Alexander R.12ORCID

Affiliation:

1. Department of Immunology and Microbiology, University of Colorado, Aurora, Colorado, USA

2. Department of Veterans Affairs, Eastern Colorado Healthcare System, Aurora, Colorado, USA

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and frequent colonizer of human skin and mucosal membranes, including the vagina, with vaginal colonization reaching nearly 25% in some pregnant populations. MRSA vaginal colonization can lead to aerobic vaginitis (AV), and during pregnancy, bacterial ascension into the upper reproductive tract can lead to adverse birth outcomes.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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