Mutants of Escherichia coli Defective in Ribonucleoside and Deoxyribonucleoside Catabolism

Author:

Karlström O.1

Affiliation:

1. Department of Chemistry II, Karolinska Institutet, Stockholm, Sweden

Abstract

From Escherichia coli B, mutants were prepared that lacked the enzymes adenosine deaminase, cytidine deaminase, and purine nucleoside phosphorylase. In each case, the mutant lacked enzyme activity for both ribonucleoside and deoxyribonucleoside. Mutants lacking purine nucleoside phosphorylase lost the capacity to cleave the nucleosides of adenine, guanine, and hypoxanthine.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference32 articles.

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4. Conjugation in Escherichia coli;BOYER H.;J. Bacteriol.,1966

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