Differential Sensitivities of Chlamydia trachomatis Strains to Inhibitory Effects of Gamma Interferon-Reference-Cited by-同舟云学术

Differential Sensitivities of Chlamydia trachomatis Strains to Inhibitory Effects of Gamma Interferon

Published:2000-10 Issue:10 Volume:68 Page:6038-6040
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Morrison Richard P.¹

Affiliation:

1. Department of Microbiology, Montana State University, Bozeman, Montana 59717

Abstract

ABSTRACT Gamma interferon (IFN-γ) is an important cytokine in host defense against chlamydial infection. An in vitro cell culture system was used to show that IFN-γ inhibition of chlamydial growth, as determined by diminished recovery of infectious elementary bodies, differed markedly among chlamydial strains. These differences in sensitivity among chlamydial strains to IFN-γ-mediated inhibition may profoundly influence the clinical outcome of infection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.68.10.6038-6040.2000

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